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And GLP-1RAs can reduce inflammatory markers and regulate endothelial function to play an anti-atherosclerosis and anti-inflammatory role (Garg et al., 2019)

Also, supplementation of sperm storage media for up to 3 days either with caffeine (71 g/ml), EGCG (82 g/ml) or l-theanine (19 g/ml) had no effect on sperm viability, while the supplementation with a combination of these three compounds significantly increased sperm viability, suggesting a synergestic effect of the components of tea rather than an individual bioactive compound 69

Animal studies have demonstrated Berberines anti-obesity mechanisms, including the inhibition of adipocyte differentiation through downregulation of adipogenic genes such as Liver X Receptors (LXRs), Peroxisome Proliferator-Activated Receptors (PPARs), and Sterol Regulatory Element-Binding Proteins (SREBPs)